Whats the simplest and quickest way to make this type of design?

[getsignups]

Good afternoon guys,

So as the title of this post reads I want to know the simplest and quickest way to make this type of design in either gimp of Inkscape.

Keep in mind I need to make some areas transparent so that the natural color of the t-shirt can come thru as seen in the design.
(The clover I am not concerned with obviously)


This will be designed for a t-shirt.

Thanks!